OU's Parnell Motley (11) celebrates with Kenneth Murray (9) during the Sooners' game against UCLA, Saturday, Sept. 8, 2018, at Oklahoma Memorial Stadium. (Kyle Phillips / The Transcript)

NORMAN, Okla. — UCLA gave Oklahoma more push than its previous opponent.

It still wasn’t near enough in the long run.

CeeDee Lamb caught seven passes for 146 yards and one touchdown, and the seventh-ranked Sooners’ defense held UCLA to one score through three quarters in a 49-21 victory Saturday.

UCLA led 7-0 after Dorian Thompson-Robinson threw a 65-yard touchdown to Caleb Wilson — whose father Chris once coached OU defensive ends – with 8:59 in the first quarter.

But OU (2-0) slowly built a big advantage. Tre Brown returned a kickoff 85 yards and set up the game-tying score, then Marquise Brown caught a 58-yard touchdown pass with 3:17 in the first to make it 21-7 Sooners.

UCLA punted four straight times going into intermission.

Lamb’s day included a handful of highlight-reel catches, including one that fell incomplete. He palmed a one-handed catch in the second half and nearly got a foot inbounds, but was called out.

His 35-yard grab in the fourth quarter put OU ahead 42-7. Moments earlier, he nearly scored on a 66-yard punt return. It helped set up a 10-yard touchdown pass to A.D. Miller.

Kyler Murray was 19-of-33 passing for 306 yards, three touchdowns and his first interception as a Sooner. He also ran for 69 yards and two scores.

OU running back Rodney Anderson appeared to injure his right knee late in the first quarter and did not return to the field. He appeared on the sideline in street clothes wearing a brace in the second half.

OU begins Big 12 play at Iowa State next Saturday (11 a.m., ABC networks).